A comprehensive assessment (more than 250 references) of how the application of evolutionary principles and approaches can improve conservation outcomes for amphibians (Pabijan et al. 2020) offers many examples and insights. A surprising number of negative effects can arise from invasive species and from introgression and hybridization, but there are also some known salutary effects. Although range fragmentation and reductions in effective population sizes can have many negative effects, it is also possible for populations to maintain genetic variability during long periods of isolation, giving hope for recovery. A table of evolutionary research questions of fundamental importance for amphibian conservation concludes this useful overview.